Company, history, milestones

Italian innovation and quality for the oral health industry

Pierrel is a global player in the pharmaceutical market, with over 70 years of experience in the field of oral care and listed at Euronext Milan of Borsa Italiana.

Pierrel is a global player in the pharmaceutical market, with over 70 years of experience in the field of oral care and listed at Euronext Milan of Borsa Italiana. Our legal and operational headquarters are in Capua, near Caserta and a few kilometers from Naples. The production facility received the first authorizations from the European Medicines Agency (EMA) in 1989 and from the Food and Drug Administration (FDA) in 2009 for the aseptic production of injectable drugs. Over the years, the core of our activity has been focused on the registration and marketing of dental anesthetics with Pierrel brand; including Orabloc,
registered in the major international markets (including USA, Canada, Italy, Russia, Poland, Serbia, France, UK, Germany, Kosovo, Austria, Sudan, Taiwan and Indonesia). Today, thanks to the FDA’s approval, we have a significant market share in the USA and we have numerous registrations going on all over the world. We also are specialized in dental research, development and distribution of medical devices.
We are one of the world’s leading manufacturers of dental anesthetics.
We are specialized in the production of dental anesthetics using aseptic technique and we work on a constant process of scouting the best medical devices for the dental sector, for which we follow directly the patent aspect, the industrialization and the commercialization, in collaboration with universities and research institutions.



The Lepetit Group founded the pharmaceutical chemical company Pierrel, dedicated to the production of antibiotics and vitamins. The name comes from the sequence pronunciation of the initials of "Prodotti Roberto Lepetit".


Starts the production of pharmaceutical specialties and medical devices.


The production of local-regional anesthetics in vials and bottles is started. We are the first in Italy to produce anesthetics in cartriges.


Our Research and Development department in Capua develops the formula of toothpaste AZ, a Pierrel product that is very successful thanks to the frequent advertising on national television networks. In these years we are engaged in the production of food supplements (Gimille, Gravigen, Generman) and shampoo (Diesse).


Pierrel sells its brad AZ to Procter & Gamble


Astrazeneca becomes the main customer of the production site.


Dentsply chooses our Capua site for the production of dental anesthetics for Europe, UK and Australia markets


We are landing on the first list (MTA) of Borsa Italiana today called Euronext Milan.


Our production site obtains the FDA (Food and Drug Administration) authorization.


Under the Pierrel brand, we start the registration and marketing of dental anaesthetics. Orabloc is launched on the American market


It is the year of the launch in the USA, Canada, UK and Italy of the medical device Goccles.


Works begins on the production site to increase the production capacity.


Unveiling of the new Inspection and Labelling department.


From the brand Orabloc comes a new medical device, Orabloc Needlestick Safety System.


Orabloc dental Needles are distributed in the U.S.